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Educate Yourself

Stromal Vascular Fraction SVF Cells


Stromal vascular fraction or SVF cells is a medical term that describes a heterogeneous kind of cell that are typically found in adipose “fat” tissue. SVF cells are not the same as “stem cells” and are generally used for cosmetic purposes. These types of cells constitute about 2/3rd of all cells in the human body.

The remaining cells are called adipocytes.(Jerareungrattan, Sila-asna, and Bunyaratvej)* SVF Cells are complex cellular products that are made from fat. SVF cell family is quite diverse and contains dozens of types of cells,cytokines and growth factors.  Stromal-vascular fraction or SVF cells include:

Adipose derived SVF cells acquired through adipose tissue are mainly used in cosmetic stem cell applications such as stem cell breast or stem cell facelifts. There are also several studies and clinical trials underway to understand the use of SVF cells in regenerative medicine for conditions such as orthopaedic sport injuries,diabetes and arthritis.(Sukpat et al. 2013)* SVF cells have demonstrated anti-inflammatory effects even using non-expanded cells.(Wang et al. 2013)*


Published Clinical Citations

  • Jerareungrattan, Aungkura, Monnipha Sila-asna, and Ahnond Bunyaratvej. Increased smooth muscle actin expression from bone marrow stromal cells under retinoic acid treatment: an attempt for autologous blood vessel tissue engineering. Asian Pacific journal of allergy and immunology, no. 2-3. http://www.ncbi.nlm.nih.gov/pubmed/16252840.
  • Sukpat, Supakanda, Nipan Isarasena, Jutamas Wongphoom, and Suthiluk Patumraj. 2013. Vasculoprotective effects of combined endothelial progenitor cells and mesenchymal stem cells in diabetic wound care: their potential role in decreasing wound-oxidative stress. BioMed research international(June 17). doi:10.1155/2013/459196. http://www.ncbi.nlm.nih.gov/pubmed/23844362.
  • Wang, Wei Z, Xin-Hua Fang, Shelley J Williams, Linda L Stephenson, Richard C Baynosa, Nancy Wong, Kayvan T Khiabani, and William A Zamboni. 2013. Analysis for apoptosis and necrosis on adipocytes, stromal vascular fraction, and adipose-derived stem cells in human lipoaspirates after liposuction. Plastic and reconstructive surgery, no. 1. doi:10.1097/PRS.0b013e3182729ff7. http://www.ncbi.nlm.nih.gov/pubmed/23271558.

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